Genomic Medicine for Improved Prediction and Primordial Prevention of Cardiovascular Disease
نویسندگان
چکیده
منابع مشابه
Genomic medicine for improved prediction and primordial prevention of cardiovascular disease.
D uring the past 10 years, large-scale genetic studies have identified hundreds of novel genetic variants for heart disease and other forms of cardiovascular (CV) disease and their risk factors. 1 Although highly successful in identifying novel genomic loci, genomic research has been criticized for its high costs, slow translation to clinical care, and many unful-filled promises. It is now clea...
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Genomic medicine and risk prediction across the disease spectrum.
Genomic medicine is based on the knowledge that virtually every medical condition, disease susceptibility or response to treatment is caused, regulated or influenced by genes. Genetic testing may therefore add value across the disease spectrum, ranging from single-gene disorders with a Mendelian inheritance pattern to complex multi-factorial diseases. The critical factors for genomic risk predi...
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In recent years, the phrase ‘genomic medicine’ has increasingly been used to describe a new development in medicine that holds great promise for human health. This new approach to health care uses the knowledge of an individual’s genetic makeup to identify those that are at a higher risk of developing certain diseases and to intervene at an earlier stage to prevent these diseases. Identifying g...
متن کاملEvidence-based medicine should be practiced for primary prevention and secondary prevention of cardiovascular disease.
Evidence-based medicine should be practiced for primary prevention and secondary prevention of cardiovascular disease. Randomized clinical trials have demonstrated, on numerous occasions, no difference or a worsening of clinical cardiovascular outcomes, whereas observational studies or studies relying on surrogate end points have shown a significant reduction in cardiovascular events by a thera...
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ژورنال
عنوان ژورنال: Arteriosclerosis, Thrombosis, and Vascular Biology
سال: 2013
ISSN: 1079-5642,1524-4636
DOI: 10.1161/atvbaha.113.301814